师资队伍

  • 姓名:黎路林
  • 职称:教授
  • 研究领域:Ø杆状病毒与宿主细胞的相互作用;Ø杆状病毒重要基因的功能解析;Ø杆状病毒基因表达调控;Ø昆虫细胞培养。
  • 联系方式:lilulin(AT)mail.ccnu.edu.cn
  • 办公室地址:5320室
  • 更多信息:

教育经历:

1978年3月 – 1981年1月:华中师范学院生物系,理学学士;

1981年3月 – 1984年12月:华中师范学院生物系,理学硕士;

1995年9月 -  2000年6月:中山大学生命科学学院,理学博士。

工作经历:

1984年12月 – 1986年6月:华中师范学院(大学)生命科学学院助教、讲师;

1986年7月 – 1993年4月:华中师范大学生命科学学院讲师;

1991年9月 – 1993年3月:英国牛津NERC环境微生物和病毒研究所访问学者;

1993年5月 – 1996年9月:华中师范大学生命科学学院副教授、硕士生导师;

1996年10月 – 2006年5月: 华中师范大学生命科学学院教授、硕士生导师;

1996年7月 – 1999年12月:美国俄勒冈州立大学微生物学系访问学者;

2000年1月 – 2002年12月: 加拿大农业和食品部太平洋研究中心博士后研究员;

2003 年1月- 2006年5月:加拿大食品检疫局动物疾病研究所研究员;

2006年6月 - 华中师范大学生命科学学院教授、博士生导师。

主要研究领域:

Ø 杆状病毒与宿主细胞的相互作用;

Ø 杆状病毒重要基因的功能解析;

Ø 杆状病毒基因表达调控;

Ø 昆虫细胞培养。

承担科研项目:

1. 国家重点研发计划项目“化学肥料和农药减施增效综合技术开发”子课题(2017YFD0200404)(2017.7-2020.12);

2. 国家自然科学基金项目(30770088):“小菜蛾颗粒体病毒晚期表达因子基因群的整体识别及其分子生物学特征研究”(2007.1-2009.12),主持;

3. 国家自然科学基金项目(30870115):“小菜蛾颗粒体病毒bacmid构建和F蛋白的功能解析”(2008.1-2010.12) 主持;

4. 国家自然科学基金项目(31170145):“苜蓿银纹夜蛾核多角体病毒ODV-E25与宿主细胞相互作用及其功能研究”(2012.1-2015.12) 主持

代表性论文:

1. Yang M, Wang S, Yue XL, Li LL*. 2014. Autographa californica Multiple Nucleopolyhedrovirus orf132 Encodes a Nucleocapsid-Associated Protein Required for Budded-Virus and Multiply Enveloped Occlusion-Derived Virus Production.J Virol. 88(21):12586-98. doi: 10.1128/JVI.01313-14. Epub 2014 Aug 20.

2. Guo YJ, Fu SH, Li LL*. Autographa californica multiple nucleopolyhedrovirus ac75 is required for egress of nucleocapsids from the nucleus and formation of de novo intranuclear membrane microvesicles. 2017. PLoS One. 12(10):e0185630. doi: 10.1371/journal.pone.0185630.

3. Ren He-Lin, Hu Yuan, Guo Ya-Jun, Li Lu-Lin*.. Plutella xylostella granulovirus late gene promoter activity in the context of the Autographa californica multiple nucleopolyhedrovirus genome. Virologica Sinica 2016,31(3):229-239.

4. Yang M, Huang C, Qian DD, Li LL*. 2014.Functional characterization of Autographa californica multiple nucleopolyhedrovirus gp16 (ac130). Virology. 464-465:341-52. doi: 10.1016/j.virol.2014.07.030. Epub 2014 Aug 9.

5. Hu Y, Li LL*.2014.The p35 and ie1 of Autographa californica multiple nucleopolyhedrovirus could rescue late gene expression of Plutella xylostella granulovirus in nonpermissive cell lines.Virus Genes. 48(2):343-55. doi: 10.1007/s11262-013-1024-x. Epub 2013 Dec 15.

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英文版:

Li, Lu-Lin

Professor

Office Address

Room 5320

Lab AddressRoom

5318

E-maillilulin(AT)mail.ccnu.edu.cn

Resume:

Academic work experience

2006-present: Professor, PhD student supervisor, College of Life Science, Central China Normal University;

1996 - 2006: Professor, MSc student supervisor, College of Life Science, Central China Normal University;

2003 – 2006: Research scientist, Animal Disease Research Institute, Food Inspection Agency, Canada;

2000 – 2002: Postdoctoral fellow, Pacific Agri-food research centre, Agriculture and Agri-food Canada.

1996 – 1999: Visiting fellow, Department of Microbiology, Oregon State University, USA;

1993 - 1996: Associate professor, MSc student supervisor, College of Life Science, Central China Normal University;

1984 - 1991: Lecturer, Entomology Institute, Central China Normal University;

1991 - 1993: Visiting fellow, NERC Institute of Virology and Environmental Microbiology, UK.

Education

1995-2000: PhD. College of Life Sciences, SUN-YAT-SEN University;

1982-1984: MSc. College of Life Sciences, Central China Normal University;

1978-1981: BSc. Department of Biology, Central China Normal University.

Research Interestes:

l Molecular virology.

l Insect cell culture engineering.

My research is currently focused on three main areas associated with baculoviruses: Interactions between virus and host insect cells; Functional characterization of individual viral genes; Regulation of viral gene expression.

Research Grants

National Natural Science Foundation of China (30770088): Identification and characterization of late expression factor genes of Plutella xylostella granulovirus. 2009-2011.

National Natural Science Foundation of China (30870115): Construction of bacmids and functional analysis on F protein of Plutella xylostella granulovirus. 2009-2011.

National Natural Science Foundation of China (31170145):Interaction between Autographa californica multiple nucleopolyhedrovirus ODV-E25 and host cells. 2012-2015.

Representative Peer-reviewed Publications:

1. Yang M, Wang S, Yue XL, Li LL*. 2014. Autographa californica Multiple Nucleopolyhedrovirus orf132 Encodes a Nucleocapsid-Associated Protein Required for Budded-Virus and Multiply Enveloped Occlusion-Derived Virus Production.J Virol. 88(21):12586-98. doi: 10.1128/JVI.01313-14. Epub 2014 Aug 20.

2. Guo YJ, Fu SH, Li LL*. Autographa californica multiple nucleopolyhedrovirus ac75 is required for egress of nucleocapsids from the nucleus and formation of de novo intranuclear membrane microvesicles. 2017. PLoS One. 12(10):e0185630. doi: 10.1371/journal.pone.0185630.

3. Ren He-Lin, Hu Yuan, Guo Ya-Jun, Li Lu-Lin*.. Plutella xylostella granulovirus late gene promoter activity in the context of the Autographa californica multiple nucleopolyhedrovirus genome. Virologica Sinica 2016,31(3):229-239.

4. Yang M, Huang C, Qian DD, Li LL*. 2014.Functional characterization of Autographa californica multiple nucleopolyhedrovirus gp16 (ac130). Virology. 464-465:341-52. doi: 10.1016/j.virol.2014.07.030. Epub 2014 Aug 9.

5. Hu Y, Li LL*.2014.The p35 and ie1 of Autographa californica multiple nucleopolyhedrovirus could rescue late gene expression of Plutella xylostella granulovirus in nonpermissive cell lines.Virus Genes. 48(2):343-55. doi: 10.1007/s11262-013-1024-x. Epub 2013 Dec 15.