教育经历： 

·2012/07-2014/05  多伦多大学，SGC 基因组中心，博士后；

·2010/03-2012/03  多伦多大学，SGC 基因组中心，博士联合培养；

·2007/09-2012/06  华中师范大学，生命科学学院，博士。 

工作经历： 

·2015/05-至 今  华中师范大学，生命科学学院，副教授；

·2012/07-2015/04  华中师范大学，生命科学学院，讲师。 

代表性论文：（*通讯作者，#共同第一作者） 

·Jin Zhang, Sizhuo Chen, Ke Liu*, Structural insights into piRNA biogenesis. Biochimica Biophysica Acta (BBA)-Gene Regulatory Mechanisms, 2022, 16;1865(2):194799.(BBA Rising Stars invited review)

·Zhibin Wu^#, Sizhuo Chen^#, Mengqi Zhou^#, Lingbo Jia, Zhenhua Li, Xiyou Zhang, Jinrong Min*, Ke Liu*, Family-wide Characterization of Methylated DNA Binding Ability of Arabidopsis MBDs. Journal of Molecular Biology, 2022, 434(2):167404.

·Sizhuo Chen^#, Mengqi Zhou^#, Aiping Dong, Peter Loppnau, Min Wang, Jinrong Min*, Ke Liu*. Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status. Journal of Biological Chemistry, 2021, 297(6):101351.

·Jinrong Min*, Ke Liu*. Structures of chromatin modulators in complex with nucleosome. Current Opinion in Chemical Biology, 2021, 63,105-114.

·Ke Liu*, Jinrong Min*. Structural basis for the recognition of non-methylated DNA by the CXXC domain. Journal of Molecular Biology, 2020, 432, 1674-1686.

·Sizhuo Chen, Weilian Zhang, Jinrong Min, Ke Liu*.  Lesson from a Fab-enabled co-crystallization study of TDRD2 and PIWIL1. Methods, 2020, 175:72-78.

·Ke Liu^#, Ming Lei^#, Zhibin Wu, Bing Gan, Harry Cheng, Yanjun Li, Jinrong Min*. Structural analyses reveal that MBD3 is a methylated CG binder. FEBS Journal, 2019, 286(16):3240-3254.

·Bing Gan, Sizhuo Chen, Huan Liu, Jinrong Min,Ke Liu*. Structure and function of eTudor domain containing TDRD proteins. Critical Reviews in Biochemistry and Molecular Biology, 2019, 54(2):119-132.

·Ming Lei, Wolfram Tempel, Sizhuo Chen, Ke Liu*，Jinrong Min*. Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. Biochimica Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2019, 1862(9):194409.

·Ke Liu^#, Chao Xu^#, Ming Lei^#, Ally Yang, Peter Loppnau, Timothy R Hughes, Jinrong Min*. Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. Journal of Biological Chemistry, 2018, 293(19):7344-7354.

·Chao Xu^#,Ke Liu^#, Ming Lei, Ally Yang, Yanjun Li, Timothy R. Hughes, Jinrong Min*. DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure, 2018, 26(1):85-95.

·Heng Zhang^#, Ke Liu^#, Natsuko Izumi^#, Haiming Huang, Deqiang Ding, Zuyao Ni, Sachdev S. Sidhu, Chen Chen, Yukihide Tomari*, Jinrong Min*. Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2. Proc Natl Acad Sci U S A (PNAS), 2017, 114(47):12483-12488.

·Dorothy yanling Zhao^#, Gerald Gish^#, Ulrich Braunschweig^#, yue Li, Zuyao Ni, Frank W. Schmitges, Guoqing Zhong,Ke Liu, Weiguo Li, Jason Moffat, Masoud Vedadi, Jinrong Min, Tony J. Pawson, Benjamin J. Blencowe, Jack F. Greenblatt*.SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Nature,2016, 529(7584):48-53.

·Chao Xu^#, Xiao Wang^#, Ke Liu^#, Ian A Roundtree, Wolfram Tempel, Yanjun Li, Zhike Lu, Chuan He*, Jinrong Min*. Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain. Nature Chemical Biology, 2014, 10(11), 927-929.

·Ke Liu, Yanli Liu, Johnathan L. Lau, Jinrong Min*. Epigenetic targets and drug discovery Part 2: Histone demethylation and DNA methylation. Pharmacology & Therapeutics, 2015, 151, 121–140.

·Yanli Liu^#, Ke Liu^#, Su Qin, Chao Xu, Jinrong Min*. Epigenetic targets and drug discovery Part 1: histone methylation. Pharmacology & Therapeutics, 2014, 143(3), 275-294.

·Ke Liu^#, Chen Chen^#, Yahong Guo^#, Robert Lam, Chuanbing Bian, Chao Xu, Dorothy Y. Zhao, Jing Jin, Farrell MacKenzie, Tony Pawson*, Jinrong Min*. Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain. Proc Natl Acad Sci U S A (PNAS), 2010, 107, 18398-18403.

主要承担科研项目：

·国家自然科学基金面上项目，编号：31770834，MIS复合物介导酵母孢子形成的分子机制研究，2018/01-2021/12，60万，主持，在研；

·湖北省自然科学基金面上项目，编号：2017CFB513，生物标记物hNGAL多价高灵敏免疫检测抗体的研发，2017/01-2018/12，3万，主持，完成；

·国家自然科学基金青年项目，编号：31300629，WDR82介导Setd1A复合物定位于基因转录起始位点进而调控基因转录的分子机理研究，2014/01-2017/12，25万，主持，完成；

·湖北省自然科学基金青年项目，编号：2013CFB206，WDR82识别SETD1A和RNA聚合酶Ⅱ磷酸化修饰CTD的分子机理研究，2013/01-2014/12，5万，主持，完成；

·华中师范大学科学技术发展研究院交叉项目，响应温度胁迫的剪接因子相关复合物的鉴定及功能分析，2016/01-2018/12，30万，主持，完成； 

荣誉或奖励：

·2014-2016  华中师范大学“三育人”先进个人；

学术任职：

·2016-2018 湖北省生物物理学会理事；

·2018-至今 湖北省武汉市生物物理学会常务理事；

·2017-至今 湖北省晶体学会理事；

·2018-至今 Current Protein & Peptide Science客座编辑，Journal of the american chemical society、Biochimica Biophysica Acta (BBA)等杂志邀请审稿人。