教育及工作经历:
2009年07月- 至今 华中师范大学 讲师、副教授、教授
2019年08月- 2020年01月 加州大学河滨分校 访问学者
2015年09月- 2016年10月 加州大学河滨分校 访问学者
2012年03月- 2012年09月 香港大学 研究助理
2004年09月- 2009年06月 山东大学 博士
主要研究领域:
1. 昆虫先天免疫与内分泌的互作机制;
2. 昆虫生殖的内分泌调控机制。
荣誉或奖励:
华中师范大学第二批学者名师支持计划“桂子青年学者”(2022)
华中师范大学第一届“嘉必优”奖教金(2024)
第九届全国大学生生命科学竞赛(2024,科学探究类) 一等奖 指导老师
第八届全国大学生生命科学竞赛(2023,科学探究类) 一等奖 指导老师
承担科研项目:
1. 国家自然科学基金面上项目(32470517):模式识别受体介导的肠道免疫调控棉铃虫20E水平和变态的分子机理,2025.01-2028.12,主持。
2. 国家自然科学基金面上项目(31872301):模式识别蛋白介导20E信号调控棉铃虫血细胞包囊的分子机理,2019.01-2022.12,主持。
3. 国家自然科学基金青年项目(31101672):棉铃虫应答20E调控体液免疫相关分子的鉴定和功能研究,2012.01-2014.12,主持。
4. 湖北省青年科技晨光计划(鄂科协办[2018]79号):蚊虫生殖控制技术与策略,主持。
5. 湖北省自然科学基金面上项目(2016CFB560):C型凝集素在棉铃虫抵御中华卵索线虫感染过程中的功能研究,2016.01-2017.12,主持。
6. 湖北省自然科学基金面上项目(2010CDB01204):基于蜕皮激素对昆虫体液免疫的调控寻找杀虫新靶标,2010.01-2011.12,主持。
7. 中央高校基本科研业务费(基础研究交叉专项,CCNU24JC026):杀虫肠道细菌次生代谢物的鉴定、合成及杀虫机理探究,2024.01-2024.12,主持。
8. 中央高校基本科研业务费(学者名师支持计划,2022):桂子青年学者,主持。
9. 中央高校基本科研业务费(探索创新类,CCNU19TS026):β-integrin介导棉铃虫血细胞包囊的分子机理,2019.04-2020.04,主持。
代表性论文:
1. Xiong P, Luo LL, Kang BY, Yao JJ, Liu XS*, Wang JL*. Tryptophan catabolism reprograms immunity to prevent hemolymph bacterial dysbiosis and support molting in Spatzle-deficient Helicoverpa armigera larvae. BMC Biology. 2026, 24:35.
2. Zhang LJ#, Zhang MM#, Liu XS, Jing YP*, Wang JL*. Starvation compromises the immunity of Helicoverpa armigera larvae by reducing 20-hydroxyecdysone levels. Entomologia Generalis. 2025, 45:797-806.
3. Wang JL#*, Zhong ZQ#, He YZ, Tian JH, Wang YF*, Raikhel AS*. The ecdysone-induced bZIP transcription factor MafB establishes a positive feedback loop to enhance vitellogenesis and reproduction in the Aedes aegypti mosquito. Proceedings of the National Academy of Sciences of the United States of America. 2025, 122:e2411688122.
4. Xiong P, Wang WW, Liu XS, Wang YF, Wang JL*. A CTL - Lys immune function maintains insect metamorphosis by preventing gut bacterial dysbiosis and limiting opportunistic infections. BMC Biology. 2024, 22:54.
5. Wang JL, Sun J, Song YJ, Zheng HH, Wang GJ, Luo WX, Li L, Liu XS*. An entomopathogenic fungus exploits its host humoral antibacterial immunity to minimize bacterial competition in the hemolymph. Microbiome. 2023, 11:116.
6. Wang JL, Yang KH, Wang SS, Li XL, Liu J, Yu YX, Liu XS*. Infection of the entomopathogenic fungus Metarhizium rileyi suppresses cellular immunity and activates humoral antibacterial immunity of the host Spodoptera frugiperda. Pest Management Science. 2022, 78:2828-2837.
7. Zhang MM, Luo LL, Liu Y, Wang GJ, Zheng HH, Liu XS, Wang JL*. Calcium and integrin-binding protein 1-like interacting with an integrin α-cytoplasmic domain facilitates cellular immunity in Helicoverpa armigera. Developmental and Comparative Immunology. 2022, 131:104379.
8. Wang GJ, Wang WW, Liu Y, Chai LQ, Wang GX, Liu XS, Wang YF, Wang JL*. Steroid hormone 20-hydroxyecdysone promotes CTL1-mediated cellular immunity in Helicoverpa armigera. Insect Science. 2021, 28:1399-1413.
9. Wang W, Wang G, Zhuo X, Liu Y, Tang L, Liu X, Wang J*. C-type lectin-mediated microbial homeostasis is critical for Helicoverpa armigera larval growth and development. PLoS Pathogens. 2020, 16:e1008901.
10. Lin Z#, Wang JL#, Cheng Y, Wang JX, Zou Z*. Pattern recognition receptors from lepidopteran insects and their biological functions. Developmental and Comparative Immunology. 2020, 108:103688.
11. Wang GJ, Zhuo XR, Wang WW, Liu XS, Wang GX, Wang JL*. Molecular characterization of immune responses of Helicoverpa armigera to infection with the mermithid nematode Ovomermis sinensis. BMC Genomics. 2019, 20:161.
12. Zhuo XR, Chen L, Wang GJ, Liu XS, Wang YF, Liu K, Yu XQ, Wang JL*. 20-Hydroxyecdysone promotes release of GBP-binding protein from oenocytoids to suppress hemocytic encapsulation. Insect Biochemistry and Molecular Biology. 2018, 92:53-64.
13. Wang JL, Saha TT, Zhang Y, Zhang C, Raikhel AS*. Juvenile hormone and its receptor methoprene-tolerant promote ribosomal biogenesis and vitellogenesis in the Aedes aegypti mosquito. Journal of Biological Chemistry. 2017, 292:10306-10315.
14. Wang P#, Zhuo XR#, Tang L, Liu XS, Wang YF, Wang GX, Yu XQ, Wang JL*. C-type lectin interacting with β-integrin enhances hemocytic encapsulation in the cotton bollworm, Helicoverpa armigera. Insect Biochemistry and Molecular Biology. 2017, 86:29-40.
15. Li J, Song CX, Li YP, Li L, Wei XH, Wang JL*, Liu XS*. 2015. Rab3 is involved in cellular immune responses of the cotton bollworm, Helicoverpa armigera. Developmental and Comparative Immunology, 50:78-86.
16. Wang JL, Chen L, Tang L, Zhao HB, Liu XS*, Wang YF*. 2014. 20-hydroxyecdysone transcriptionally regulates humoral immunity in the fat body of Helicoverpa armigera. Insect Molecular Biology, 23:842-856.
17. Liu C#, Wang JL#, Zheng Y, Xiong EJ, Li JJ, Yuan LL, Yu XQ, Wang YF*. 2014. Wolbachia-induced paternal defect in Drosophila is likely by interaction with the juvenile hormone pathway. Insect Biochemistry and Molecular Biology, 49:49-58.
18. Wang JL*, Zhang Q, Tang L, Chen L, Liu XS, Wang YF*. 2014. Involvement of a pattern recognition receptor C-type lectin 7 in enhancing cellular encapsulation and melanization due to its carboxyl-terminal CRD domain in the cotton bollworm, Helicoverpa armigera. Developmental and Comparative Immunology, 44:21-29.
19. Wang JL*, Liu XS, Zhang Q, Zhao HB, Wang YF*. 2012. Expression profiles of six novel C-type lectins in response to bacterial and 20E injection in the cotton bollworm (Helicoverpa armigera). Developmental and Comparative Immunology, 37:221-232.
20. Zheng Y#, Wang JL#, Liu C, Wang CP, Walker T, Wang YF*. 2011. Differentially expressed profiles in the larval testes of Wolbachia infected and uninfected Drosophila. BMC Genomics, 12:595.
学术兼职:
武汉市动物学会理事(2023.05-)
湖北省昆虫学会理事(2018.10-)

